Which two fingers are most commonly involved in Dupuytren's contracture?

The correct answer identifies the little and ring fingers as the most commonly involved in Dupuytren's contracture. This condition is characterized by the thickening and shortening of the palmar fascia, which leads to the flexion of the fingers, particularly affecting the little and ring fingers. This tends to happen because the condition primarily impacts the tendons and connective tissue in the palm of the hand, where the contracture typically forms.

The anatomy of hand function also supports this, as these two fingers are less actively involved in precision grip compared to the index and middle fingers. The involvement of the little and ring fingers is a significant clinical observation, as it affects hand function and can lead to challenges in daily activities.

In contrast, while other fingers can be affected, conditions like Dupuytren's contracture are less commonly associated with the thumb and index fingers or the middle finger. Understanding the specific involvement of the little and ring fingers helps in both diagnosis and treatment approaches for individuals suffering from this condition.